Domperidone for nausea and vomiting: lack of efficacy in children; reminder of contraindications in adults and adolescents
A European review has assessed new evidence (in gastroenteritis) that domperidone is not as effective as previously considered. Consequently, the product information for UK domperidone medicines has been updated to remove the indication in children younger than 12 years of age.
“If a specialist physician considers, based on their professional judgement and available evidence of the medical condition, that domperidone use in any condition is justified in a child younger than 12 years, the patient or parent/caregiver should be fully informed of the potential benefits and risks of the different options.”